Human SPINK2 activation kit by CRISPRa

CAT#: GA104591

SPINK2 CRISPRa kit - CRISPR gene activation of human serine peptidase inhibitor, Kazal type 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SPINK2
• Locus ID: 6691
• Kit Components:

  GA104591G1, SPINK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104591G2, SPINK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104591G3, SPINK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001271718, NM_001271719, NM_001271720, NM_001271721, NM_001271722, NM_021114, NR_073417, NR_073418, NR_073419
• Synonyms: HUSI-II
• Summary: 'This gene encodes a member of the family of serine protease inhibitors of the Kazal type (SPINK). The encoded protein acts as a trypsin and acrosin inhibitor in the genital tract and is localized in the spermatozoa. The protein has been associated with the progression of lymphomas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]'