Human Aurora C (AURKC) activation kit by CRISPRa

CAT#: GA104680

AURKC CRISPRa kit - CRISPR gene activation of human aurora kinase C

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AURKC
• Locus ID: 6795
• Kit Components:

  GA104680G1, Aurora C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104680G2, Aurora C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104680G3, Aurora C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001015878, NM_001015879, NM_003160
• Synonyms: AIE2; AIK3; ARK3; AurC; aurora-C; HEL-S-90; SPGF5; STK13
• Summary: 'This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]'