Human Suppressor of Ty 4 homolog 1 (SUPT4H1) activation kit by CRISPRa

CAT#: GA104697

SUPT4H1 CRISPRa kit - CRISPR gene activation of human SPT4 homolog, DSIF elongation factor subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SUPT4H1
• Locus ID: 6827
• Kit Components:

  GA104697G1, Suppressor of Ty 4 homolog 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104697G2, Suppressor of Ty 4 homolog 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104697G3, Suppressor of Ty 4 homolog 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003168, NR_073470
• Synonyms: SPT4; SPT4H; Supt4a; SUPT4H
• Summary: 'This gene encodes the small subunit of DRB (5,6-dichloro-1-beta-d-ribofuranosylbenzimidazole) sensitivity-inducing factor (DSIF) complex, which regulates mRNA processing and transcription elongation by RNA polymerase II. The encoded protein is localized to the nucleus and interacts with the large subunit (SUPT5H) to form the DSIF complex. Related pseudogenes have been identified on chromosomes 2 and 12. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]'