Human TRF2 (TERF2) activation kit by CRISPRa

CAT#: GA104824

TERF2 CRISPRa kit - CRISPR gene activation of human telomeric repeat binding factor 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TERF2
• Locus ID: 7014
• Kit Components:

  GA104824G1, TRF2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104824G2, TRF2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104824G3, TRF2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005652
• Synonyms: TRBF2; TRF2
• Summary: 'This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic. [provided by RefSeq, Jul 2008]'