Human AP2 alpha (TFAP2A) activation kit by CRISPRa

CAT#: GA104829

TFAP2A CRISPRa kit - CRISPR gene activation of human transcription factor AP-2 alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFAP2A
• Locus ID: 7020
• Kit Components:

  GA104829G1, AP2 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104829G2, AP2 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104829G3, AP2 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001032280, NM_001042425, NM_003220
• Synonyms: AP-2; AP-2alpha; AP2TF; BOFS; TFAP2
• Summary: 'The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]'