Human TFAP4 activation kit by CRISPRa

CAT#: GA104832

TFAP4 CRISPRa kit - CRISPR gene activation of human transcription factor AP-4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TFAP4
• Locus ID: 7023
• Kit Components:

  GA104832G1, TFAP4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104832G2, TFAP4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104832G3, TFAP4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003223
• Synonyms: AP-4; bHLHc41
• Summary: 'Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]'