Human TLL1 activation kit by CRISPRa

CAT#: GA104893

TLL1 CRISPRa kit - CRISPR gene activation of human tolloid like 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TLL1
• Locus ID: 7092
• Kit Components:

  GA104893G1, TLL1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA104893G2, TLL1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA104893G3, TLL1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001204760, NM_012464
• Synonyms: ASD6; TLL
• Summary: This gene encodes an astacin-like, zinc-dependent, metalloprotease that belongs to the peptidase M12A family. This protease processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Studies in mice suggest that this gene plays multiple roles in the development of mammalian heart, and is essential for the formation of the interventricular septum. Allelic variants of this gene are associated with atrial septal defect type 6. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]