Human TSPAN4 activation kit by CRISPRa

CAT#: GA104907

TSPAN4 CRISPRa kit - CRISPR gene activation of human tetraspanin 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TSPAN4
• Locus ID: 7106
• Kit Components:

  GA104907G1, TSPAN4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104907G2, TSPAN4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104907G3, TSPAN4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025234, NM_001025235, NM_001025236, NM_001025237, NM_001025238, NM_001025239, NM_003271
• Synonyms: NAG-2; NAG2; TETRASPAN; TM4SF7; TSPAN-4
• Summary: 'The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'