Human Thyrotropin Releasing Hormone (TRH) activation kit by CRISPRa

CAT#: GA104972

TRH CRISPRa kit - CRISPR gene activation of human thyrotropin releasing hormone

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRH
• Locus ID: 7200
• Kit Components:

  GA104972G1, Thyrotropin Releasing Hormone gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104972G2, Thyrotropin Releasing Hormone gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104972G3, Thyrotropin Releasing Hormone gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_007117
• Synonyms: Pro-TRH; TRF
• Summary: 'This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The human proprotein contains six thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Deficiency of this hormone has been associated with hypothalamic hypothyroidism. [provided by RefSeq, May 2013]'