Human TRPC3 activation kit by CRISPRa

CAT#: GA104979

TRPC3 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily C member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPC3
• Locus ID: 7222
• Kit Components:

  GA104979G1, TRPC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104979G2, TRPC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104979G3, TRPC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130698, NM_003305, NM_001366479
• Synonyms: SCA41; TRP3
• Summary: 'The protein encoded by this gene is a membrane protein that can form a non-selective channel permeable to calcium and other cations. The encoded protein appears to be induced to form channels by a receptor tyrosine kinase-activated phosphatidylinositol second messenger system and also by depletion of intracellular calcium stores. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]'