Human TRPM2 activation kit by CRISPRa

CAT#: GA104983

TRPM2 CRISPRa kit - CRISPR gene activation of human transient receptor potential cation channel subfamily M member 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: TRPM2
• Locus ID: 7226
• Kit Components:

  GA104983G1, TRPM2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA104983G2, TRPM2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA104983G3, TRPM2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001188, NM_003307, NR_038257, NM_001320350, NM_001320351, NM_001320352
• Synonyms: EREG1; KNP3; LTRPC2; MGC133383; NUDT9H; NUDT9L1; TRPC7
• Summary: 'The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]'