Human U2AF35 (U2AF1) activation kit by CRISPRa

CAT#: GA105033

U2AF1 CRISPRa kit - CRISPR gene activation of human U2 small nuclear RNA auxiliary factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: U2AF1
• Locus ID: 7307
• Kit Components:

  GA105033G1, U2AF35 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105033G2, U2AF35 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105033G3, U2AF35 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001025203, NM_001025204, NM_006758
• Synonyms: FP793; RN; RNU2AF1; U2AF35; U2AFBP
• Summary: 'This gene belongs to the splicing factor SR family of genes. U2 auxiliary factor, comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]'