Human UBE2I activation kit by CRISPRa

CAT#: GA105049

UBE2I CRISPRa kit - CRISPR gene activation of human ubiquitin conjugating enzyme E2 I

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: UBE2I
• Locus ID: 7329
• Kit Components:

  GA105049G1, UBE2I gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105049G2, UBE2I gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105049G3, UBE2I gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003345, NM_194259, NM_194260, NM_194261
• Synonyms: C358B7.1; P18; UBC9
• Summary: 'The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Four alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]'