Human USP1 activation kit by CRISPRa

CAT#: GA105096

USP1 CRISPRa kit - CRISPR gene activation of human ubiquitin specific peptidase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: USP1
• Locus ID: 7398
• Kit Components:

  GA105096G1, USP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105096G2, USP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105096G3, USP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001017415, NM_001017416, NM_003368
• Synonyms: UBP
• Summary: 'This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]'