Human CLRN1 activation kit by CRISPRa

CAT#: GA105098

CLRN1 CRISPRa kit - CRISPR gene activation of human clarin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CLRN1
• Locus ID: 7401
• Kit Components:

  GA105098G1, CLRN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105098G2, CLRN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105098G3, CLRN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001195794, NM_001256819, NM_052995, NM_174878, NM_174880, NR_046380
• Synonyms: RP61; USH3; USH3A
• Summary: 'This gene encodes a protein that contains a cytosolic N-terminus, multiple helical transmembrane domains, and an endoplasmic reticulum membrane retention signal, TKGH, in the C-terminus. The encoded protein may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIIa. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]'