Human YES1 activation kit by CRISPRa

CAT#: GA105179

YES1 CRISPRa kit - CRISPR gene activation of human YES proto-oncogene 1, Src family tyrosine kinase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: YES1
• Locus ID: 7525
• Kit Components:

  GA105179G1, YES1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105179G2, YES1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105179G3, YES1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005433
• Synonyms: c-yes; HsT441; P61-YES; Yes
• Summary: 'This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. [provided by RefSeq, Jul 2008]'