Human ZKSCAN1 activation kit by CRISPRa

CAT#: GA105223

ZKSCAN1 CRISPRa kit - CRISPR gene activation of human zinc finger with KRAB and SCAN domains 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZKSCAN1
• Locus ID: 7586
• Kit Components:

  GA105223G1, ZKSCAN1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105223G2, ZKSCAN1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105223G3, ZKSCAN1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001287054, NM_001287055, NM_003439, NM_001346579, NM_001346580, NM_001346581, NR_144477
• Synonyms: 9130423L19Rik; KOX18; PHZ-37; ZNF36; ZNF139; ZSCAN33
• Summary: 'This gene encodes a member of the Kruppel C2H2-type zinc-finger family of proteins. This encoded protein may function as a transcription factor that regulates the expression of GABA type-A receptors in the brain. Transcripts from this gene have been shown to form stable and abundant circular RNAs. Elevated expression of this gene has been observed in gastric cancer and the encoded protein may stimulate migration and invasion of human gastric cancer cells. [provided by RefSeq, Oct 2016]'