Human ZNF185 activation kit by CRISPRa

CAT#: GA105281

ZNF185 CRISPRa kit - CRISPR gene activation of human zinc finger protein 185 with LIM domain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZNF185
• Locus ID: 7739
• Kit Components:

  GA105281G1, ZNF185 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105281G2, ZNF185 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105281G3, ZNF185 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001178106, NM_001178107, NM_001178108, NM_001178109, NM_001178110, NM_001178113, NM_001178114, NM_001178115, NM_007150
• Synonyms: SCELL
• Summary: 'Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This gene encodes a LIM-domain zinc finger protein. The LIM domain is composed of two contiguous zinc finger domains, separated by a two-amino acid residue hydrophobic linker. The LIM domain mediates protein:protein interactions. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, May 2010]'