Human ZNF202 activation kit by CRISPRa

CAT#: GA105289

ZNF202 CRISPRa kit - CRISPR gene activation of human zinc finger protein 202

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZNF202
• Locus ID: 7753
• Kit Components:

  GA105289G1, ZNF202 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105289G2, ZNF202 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105289G3, ZNF202 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301779, NM_001301780, NM_001301819, NM_003455
• Synonyms: ZKSCAN10; ZSCAN42
• Summary: Transcriptional repressor that binds to elements found predominantly in genes that participate in lipid metabolism. Among its targets are structural components of lipoprotein particles (apolipoproteins AIV, CIII, and E), enzymes involved in lipid processing (lipoprotein lipase, lecithin cholesteryl ester transferase), transporters involved in lipid homeostasis (ABCA1, ABCG1), and several genes involved in processes related to energy metabolism and vascular disease. [UniProtKB/Swiss-Prot Function]