Human DEK activation kit by CRISPRa

CAT#: GA105352

DEK CRISPRa kit - CRISPR gene activation of human DEK proto-oncogene

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DEK
• Locus ID: 7913
• Kit Components:

  GA105352G1, DEK gRNA vector 1 in pCas-Guide-CRISPRa

  GA105352G2, DEK gRNA vector 2 in pCas-Guide-CRISPRa

  GA105352G3, DEK gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001134709, NM_003472
• Synonyms: D6S231E
• Summary: This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]