Human OGR1 (GPR68) activation kit by CRISPRa

CAT#: GA105415

GPR68 CRISPRa kit - CRISPR gene activation of human G protein-coupled receptor 68

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPR68
• Locus ID: 8111
• Kit Components:

  GA105415G1, GPR68 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105415G2, GPR68 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105415G3, GPR68 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177676, NM_003485, NM_001348437
• Synonyms: GPR12A; OGR1
• Summary: The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta. [provided by RefSeq, Feb 2017]