Human ST8SIA2 activation kit by CRISPRa

CAT#: GA105419

ST8SIA2 CRISPRa kit - CRISPR gene activation of human ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ST8SIA2
• Locus ID: 8128
• Kit Components:

  GA105419G1, ST8SIA2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105419G2, ST8SIA2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105419G3, ST8SIA2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006011, NM_001330416
• Synonyms: HsT19690; SIAT8B; ST8SIA-II; STX
• Summary: The protein encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29. [provided by RefSeq, Jul 2008]