Human AKAP1 activation kit by CRISPRa

CAT#: GA105426

AKAP1 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKAP1
• Locus ID: 8165
• Kit Components:

  GA105426G1, AKAP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105426G2, AKAP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105426G3, AKAP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001242902, NM_001242903, NM_003488, NM_139275, NM_001370426, NM_001370427, NM_001370423, NM_001370424, NM_001370425
• Synonyms: AKAP; AKAP84; AKAP121; AKAP149; D-AKAP1; PPP1R43; PRKA1; SAKAP84; TDRD17
• Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]