Human EOMES activation kit by CRISPRa

CAT#: GA105485

EOMES CRISPRa kit - CRISPR gene activation of human eomesodermin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EOMES
• Locus ID: 8320
• Kit Components:

  GA105485G1, EOMES gRNA vector 1 in pCas-Guide-CRISPRa

  GA105485G2, EOMES gRNA vector 2 in pCas-Guide-CRISPRa

  GA105485G3, EOMES gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001278182, NM_001278183, NM_005442
• Synonyms: TBR2
• Summary: This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]