Human RAD54 (RAD54L) activation kit by CRISPRa

CAT#: GA105572

RAD54L CRISPRa kit - CRISPR gene activation of human RAD54 like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: RAD54L
• Locus ID: 8438
• Kit Components:

  GA105572G1, RAD54L gRNA vector 1 in pCas-Guide-CRISPRa

  GA105572G2, RAD54L gRNA vector 2 in pCas-Guide-CRISPRa

  GA105572G3, RAD54L gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001142548, NM_003579, NM_001370766
• Synonyms: hHR54; HR54; hRAD54; RAD54A
• Summary: The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Dec 2008]