RAD54 (RAD54L) Human Gene Knockout Kit (CRISPR)
CAT#: KN420046
RAD54L - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.
KN2.0 knockout kit validation
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 2 gRNA vectors, 1 linear donor |
Donor DNA | EF1a-GFP-P2A-Puro |
Symbol | RAD54L |
Locus ID | 8438 |
Disclaimer | The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process. |
Reference Data | |
RefSeq | NM_001142548, NM_003579, NM_001370766 |
Synonyms | hHR54; HR54; hRAD54; RAD54A |
Summary | The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Dec 2008] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
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KN220046 | RAD54L - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN220046BN | RAD54L - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN220046LP | RAD54L - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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KN220046RB | RAD54L - human gene knockout kit via CRISPR, HDR mediated |
USD 1,290.00 |
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GA105572 | RAD54L CRISPRa kit - CRISPR gene activation of human RAD54 like |
USD 1,290.00 |
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