Human FKLF / KLF11 (KLF11) activation kit by CRISPRa

CAT#: GA105592

KLF11 CRISPRa kit - CRISPR gene activation of human Kruppel like factor 11


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol KLF11
Locus ID 8462
Kit Components

GA105592G1, KLF11 gRNA vector 1 in pCas-Guide-CRISPRa

GA105592G2, KLF11 gRNA vector 2 in pCas-Guide-CRISPRa

GA105592G3, KLF11 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001177716, NM_001177718, NM_003597
Synonyms FKLF; FKLF1; MODY7; TIEG2; Tieg3
Summary The protein encoded by this gene is a zinc finger transcription factor that binds to SP1-like sequences in epsilon- and gamma-globin gene promoters. This binding inhibits cell growth and causes apoptosis. Defects in this gene are a cause of maturity-onset diabetes of the young type 7 (MODY7). Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.