Human GCM1 activation kit by CRISPRa

CAT#: GA105637

GCM1 CRISPRa kit - CRISPR gene activation of human glial cells missing transcription factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GCM1
• Locus ID: 8521
• Kit Components:

  GA105637G1, GCM1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105637G2, GCM1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105637G3, GCM1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003643
• Synonyms: GCMA; hGCMa
• Summary: This gene encodes a DNA-binding protein with a gcm-motif (glial cell missing motif). The encoded protein is a homolog of the Drosophila glial cells missing gene (gcm). This protein binds to the GCM-motif (A/G)CCCGCAT, a novel sequence among known targets of DNA-binding proteins. The N-terminal DNA-binding domain confers the unique DNA-binding activity of this protein. [provided by RefSeq, Jul 2008]