Human CPNE1 activation kit by CRISPRa

CAT#: GA105932

CPNE1 CRISPRa kit - CRISPR gene activation of human copine 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CPNE1
• Locus ID: 8904
• Kit Components:

  GA105932G1, CPNE1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105932G2, CPNE1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105932G3, CPNE1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001198863, NM_003915, NM_152925, NM_152926, NM_152927, NM_152928, NM_152929, NM_152930, NM_152931, NR_037188
• Synonyms: COPN1; CPN1
• Summary: Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Alternate splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Aug 2008]