Human CACNA1I activation kit by CRISPRa

CAT#: GA105939

CACNA1I CRISPRa kit - CRISPR gene activation of human calcium voltage-gated channel subunit alpha1 I

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CACNA1I
• Locus ID: 8911
• Kit Components:

  GA105939G1, CACNA1I gRNA vector 1 in pCas-Guide-CRISPRa

  GA105939G2, CACNA1I gRNA vector 2 in pCas-Guide-CRISPRa

  GA105939G3, CACNA1I gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001003406, NM_021096, N52765
• Synonyms: ca(v)3.3; Cav3.3
• Summary: This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]