Human Selenium Binding Protein 1 (SELENBP1) activation kit by CRISPRa

CAT#: GA105978

SELENBP1 CRISPRa kit - CRISPR gene activation of human selenium binding protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SELENBP1
• Locus ID: 8991
• Kit Components:

  GA105978G1, SELENBP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105978G2, SELENBP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105978G3, SELENBP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001258288, NM_001258289, NM_003944
• Synonyms: HEL-S-134P; hSBP; LPSB; SBP56; SP56
• Summary: This gene encodes a member of the selenium-binding protein family. Selenium is an essential nutrient that exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. The effects of selenium in preventing cancer and neurologic diseases may be mediated by selenium-binding proteins, and decreased expression of this gene may be associated with several types of cancer. The encoded protein may play a selenium-dependent role in ubiquitination/deubiquitination-mediated protein degradation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]