Human Proteinase Activated Receptor 4 (F2RL3) activation kit by CRISPRa

CAT#: GA105987

F2RL3 CRISPRa kit - CRISPR gene activation of human F2R like thrombin or trypsin receptor 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: F2RL3
• Locus ID: 9002
• Kit Components:

  GA105987G1, F2RL3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA105987G2, F2RL3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA105987G3, F2RL3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003950
• Synonyms: PAR4
• Summary: This gene encodes a member of the protease-activated receptor subfamily, part of the G-protein coupled receptor 1 family of proteins. The encoded receptor is proteolytically processed to reveal an extracellular N-terminal tethered ligand that binds to and activates the receptor. This receptor plays a role in blood coagulation, inflammation and response to pain. Hypomethylation at this gene may be associated with lung cancer in human patients. [provided by RefSeq, Sep 2016]