Human CH25H activation kit by CRISPRa

CAT#: GA105996

CH25H CRISPRa kit - CRISPR gene activation of human cholesterol 25-hydroxylase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CH25H
• Locus ID: 9023
• Kit Components:

  GA105996G1, CH25H gRNA vector 1 in pCas-Guide-CRISPRa

  GA105996G2, CH25H gRNA vector 2 in pCas-Guide-CRISPRa

  GA105996G3, CH25H gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_003956
• Synonyms: C25H
• Summary: This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008]