Human CCRL2 activation kit by CRISPRa

CAT#: GA106005

CCRL2 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine receptor like 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CCRL2
• Locus ID: 9034
• Kit Components:

  GA106005G1, CCRL2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106005G2, CCRL2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106005G3, CCRL2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130910, NM_003965
• Synonyms: ACKR5; CKRX; CRAM; CRAM-A; CRAM-B; HCR
• Summary: This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]