Human P2X6 (P2RX6) activation kit by CRISPRa

CAT#: GA106080

P2RX6 CRISPRa kit - CRISPR gene activation of human purinergic receptor P2X 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P2RX6
• Locus ID: 9127
• Kit Components:

  GA106080G1, P2RX6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106080G2, P2RX6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106080G3, P2RX6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001159554, NM_005446, NM_001349874, NM_001349875, NM_001349876
• Synonyms: P2RXL1; P2X6; P2XM
• Summary: The protein encoded by this gene belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified. [provided by RefSeq, Apr 2009]