Human SLC33A1 activation kit by CRISPRa

CAT#: GA106131

SLC33A1 CRISPRa kit - CRISPR gene activation of human solute carrier family 33 member 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SLC33A1
• Locus ID: 9197
• Kit Components:

  GA106131G1, SLC33A1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106131G2, SLC33A1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106131G3, SLC33A1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190992, NM_004733, NM_001363883
• Synonyms: ACATN; AT-1; AT1; CCHLND; SPG42
• Summary: The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]