Human SFRS11 (SRSF11) activation kit by CRISPRa

CAT#: GA106198

SRSF11 CRISPRa kit - CRISPR gene activation of human serine and arginine rich splicing factor 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: SRSF11
• Locus ID: 9295
• Kit Components:

  GA106198G1, SRSF11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106198G2, SRSF11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106198G3, SRSF11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001190987, NM_004768, NM_001350605, NM_001350606, NM_001350607, NM_001350608, NM_001350609, NM_001350610, NM_001350611, NM_001350612, NM_001350613, NM_001350614, NM_001350615, NM_001350616, NR_146810
• Synonyms: dJ677H15.2; NET2; p54; SFRS11
• Summary: This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12. [provided by RefSeq, Sep 2010]