SFRS11 (SRSF11) Human Gene Knockout Kit (CRISPR)

CAT#: KN408055

SRSF11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated.

Product Images

Specifications

Product Data

• Format: 2 gRNA vectors, 1 linear donor
• Donor DNA: EF1a-GFP-P2A-Puro
• Symbol: SRSF11
• Locus ID: 9295
• Disclaimer: The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.

Reference Data

• RefSeq: NM_001190987, NM_004768, NM_001350605, NM_001350606, NM_001350607, NM_001350608, NM_001350609, NM_001350610, NM_001350611, NM_001350612, NM_001350613, NM_001350614, NM_001350615, NM_001350616, NR_146810
• Synonyms: dJ677H15.2; NET2; p54; SFRS11
• Summary: This gene encodes 54-kD nuclear protein that contains an arginine/serine-rich region similar to segments found in pre-mRNA splicing factors. Although the function of this protein is not yet known, structure and immunolocalization data suggest that it may play a role in pre-mRNA processing. Alternative splicing results in multiple transcript variants encoding different proteins. In addition, a pseudogene of this gene has been found on chromosome 12. [provided by RefSeq, Sep 2010]