Human Smad Interacting Protein 1 (ZEB2) activation kit by CRISPRa

CAT#: GA106632

ZEB2 CRISPRa kit - CRISPR gene activation of human zinc finger E-box binding homeobox 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZEB2
• Locus ID: 9839
• Kit Components:

  GA106632G1, ZEB2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106632G2, ZEB2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106632G3, ZEB2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001171653, NM_014795, NR_033258
• Synonyms: HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
• Summary: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010]