Human GPR105 (P2RY14) activation kit by CRISPRa

CAT#: GA106717

P2RY14 CRISPRa kit - CRISPR gene activation of human purinergic receptor P2Y14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: P2RY14
• Locus ID: 9934
• Kit Components:

  GA106717G1, P2RY14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106717G2, P2RY14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106717G3, P2RY14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081455, NM_014879
• Synonyms: BPR105; GPR105; P2Y14
• Summary: The product of this gene belongs to the family of G-protein coupled receptors, which contains several receptor subtypes with different pharmacological selectivity for various adenosine and uridine nucleotides. This receptor is a P2Y purinergic receptor for UDP-glucose and other UDP-sugars coupled to G-proteins. It has been implicated in extending the known immune system functions of P2Y receptors by participating in the regulation of the stem cell compartment, and it may also play a role in neuroimmune function. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]