Human Glypican 6 (GPC6) activation kit by CRISPRa

CAT#: GA106834

GPC6 CRISPRa kit - CRISPR gene activation of human glypican 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: GPC6
• Locus ID: 10082
• Kit Components:

  GA106834G1, GPC6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106834G2, GPC6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106834G3, GPC6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005708
• Synonyms: OMIMD1
• Summary: The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1. [provided by RefSeq, Nov 2016]