Human BAP31 (BCAP31) activation kit by CRISPRa

CAT#: GA106877

BCAP31 CRISPRa kit - CRISPR gene activation of human B cell receptor associated protein 31

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: BCAP31
• Locus ID: 10134
• Kit Components:

  GA106877G1, BCAP31 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106877G2, BCAP31 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106877G3, BCAP31 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001139441, NM_001139457, NM_001256447, NM_005745, NR_024450
• Synonyms: 6C6-AG; BAP31; CDM; DDCH; DXS1357E
• Summary: This gene encodes a member of the B-cell receptor associated protein 31 superfamily. The encoded protein is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in caspase 8-mediated apoptosis. Microdeletions in this gene are associated with contiguous ABCD1/DXS1375E deletion syndrome (CADDS), a neonatal disorder. Alternative splicing of this gene results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 16. [provided by RefSeq, Jan 2012]