Human ZMPSTE24 activation kit by CRISPRa

CAT#: GA106993

ZMPSTE24 CRISPRa kit - CRISPR gene activation of human zinc metallopeptidase STE24

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: ZMPSTE24
• Locus ID: 10269
• Kit Components:

  GA106993G1, ZMPSTE24 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106993G2, ZMPSTE24 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106993G3, ZMPSTE24 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005857
• Synonyms: FACE-1; FACE1; HGPS; PRO1; STE24; Ste24p
• Summary: This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]