Human AKAP8 activation kit by CRISPRa

CAT#: GA106994

AKAP8 CRISPRa kit - CRISPR gene activation of human A-kinase anchoring protein 8

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: AKAP8
• Locus ID: 10270
• Kit Components:

  GA106994G1, AKAP8 gRNA vector 1 in pCas-Guide-CRISPRa

  GA106994G2, AKAP8 gRNA vector 2 in pCas-Guide-CRISPRa

  GA106994G3, AKAP8 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_005858
• Synonyms: AKAP-8; AKAP-95; AKAP 95; AKAP95
• Summary: This gene encodes a member of the A-kinase anchor protein family. A-kinase anchor proteins are scaffold proteins that contain a binding domain for the RI/RII subunit of protein kinase A (PKA) and recruit PKA and other signaling molecules to specific subcellular locations. This gene encodes a nuclear A-kinase anchor protein that binds to the RII alpha subunit of PKA and may play a role in chromosome condensation during mitosis by targeting PKA and the condensin complex to chromatin. A pseudogene of this gene is located on the short arm of chromosome 9. [provided by RefSeq, May 2011]