Human APBB3 activation kit by CRISPRa

CAT#: GA107022

APBB3 CRISPRa kit - CRISPR gene activation of human amyloid beta precursor protein binding family B member 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: APBB3
• Locus ID: 10307
• Kit Components:

  GA107022G1, APBB3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107022G2, APBB3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107022G3, APBB3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006051, NM_133172, NM_133173, NM_133174, NM_133175, NM_133176
• Synonyms: FE65L2; SRA
• Summary: The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]