Human KBTBD10 (KLHL41) activation kit by CRISPRa

CAT#: GA107036

KLHL41 CRISPRa kit - CRISPR gene activation of human kelch like family member 41

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: KLHL41
• Locus ID: 10324
• Kit Components:

  GA107036G1, KLHL41 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107036G2, KLHL41 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107036G3, KLHL41 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_006063
• Synonyms: KBTBD10; Krp1; SARCOSIN
• Summary: This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. [provided by RefSeq, Mar 2015]