Human CITED2 activation kit by CRISPRa

CAT#: GA107066

CITED2 CRISPRa kit - CRISPR gene activation of human Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: CITED2
• Locus ID: 10370
• Kit Components:

  GA107066G1, CITED2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107066G2, CITED2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107066G3, CITED2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001168388, NM_001168389, NM_006079
• Synonyms: ASD8; MRG-1; MRG1; P35SRJ; VSD2
• Summary: The protein encoded by this gene inhibits transactivation of HIF1A-induced genes by competing with binding of hypoxia-inducible factor 1-alpha to p300-CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]