Human DLC1 activation kit by CRISPRa

CAT#: GA107083

DLC1 CRISPRa kit - CRISPR gene activation of human DLC1 Rho GTPase activating protein

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: DLC1
• Locus ID: 10395
• Kit Components:

  GA107083G1, DLC1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107083G2, DLC1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107083G3, DLC1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001164271, NM_001316668, NM_006094, NM_024767, NM_182643, NM_001348081, NM_001348082, NM_001348083, NM_001348084
• Synonyms: ARHGAP7; HP; p122-RhoGAP; STARD12
• Summary: This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene. [provided by RefSeq, Apr 2010]