Human YAP1 activation kit by CRISPRa

CAT#: GA107099

YAP1 CRISPRa kit - CRISPR gene activation of human Yes associated protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: YAP1
• Locus ID: 10413
• Kit Components:

  GA107099G1, YAP1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107099G2, YAP1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107099G3, YAP1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001130145, NM_001195044, NM_001195045, NM_001282097, NM_001282098, NM_001282099, NM_001282100, NM_001282101, NM_006106
• Synonyms: COB1; YAP; YAP2; YAP65; YKI
• Summary: This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2013]