Human EMG1 activation kit by CRISPRa

CAT#: GA107116

EMG1 CRISPRa kit - CRISPR gene activation of human EMG1 N1-specific pseudouridine methyltransferase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: EMG1
• Locus ID: 10436
• Kit Components:

  GA107116G1, EMG1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA107116G2, EMG1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA107116G3, EMG1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001320049, NM_006331, NR_135131
• Synonyms: C2F; Grcc2f; NEP1
• Summary: This gene encodes an essential, conserved eukaryotic protein that methylates pseudouridine in 18S rRNA. The related protein in yeast is a component of the small subunit processome and is essential for biogenesis of the ribosomal 40S subunit. A mutation in this gene has been associated with Bowen-Conradi syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]